主要研究方向为“先进钢铁结构材料设计、制备、表征与使役行为”，即基于先进钢铁结构材料的强韧化、耐热、耐腐蚀、抗辐照、抗疲劳及耐微生物腐蚀功能化等方面的成分组织和性能设计的金属学基础和热机械加工工艺学基础与应用研究。具体涉及2类先进钢铁结构材料：
1、基于碳中和二氧化碳排放达标的现代及未来核能（聚变能、快堆）火电（超超临界、超高临界）用耐高温、耐腐蚀、抗辐照用耐热钢的成分、组织性能设计冶金学及热加工工艺基础与应用研究；
基于石油天然气能源开发应用的输送用系列管线钢的强韧化、超低温韧性、超细晶、抗大变形、耐硫化氢及耐微生物腐蚀功能一体化的冶金学及热加工工艺基础与应用研究。

发表学术论文210余篇，申请专利50余项，获得授权发明专利30余项，中英文专著2部，国家标准3项。
出版著作和国家标准：
1、“9-12Cr Heat-Resistant Steels”, Wei Yan, Wei Wang, Yiyin Shan, Ke Yang, Wei Sha. Engineering Materials, Springger. ISSN 1612-1317. 2015。
2、超细晶粒钢——钢的组织细化理论与控制技术，翁宇庆等。第二篇第3、4章，杨柯，单以银 P.333-407. 冶金工业出版社。
3、单以银, 石全强, 卢伦, 王志光, 戴强, 严伟, 崔鸿, 王威, 姚存峰, 杨柯, 李艳芬, 黄群英, 胡进，《核电用耐高温抗腐蚀低活化马氏体结构钢》，GB/T38875-2020，中华人民共和国国家标准。
4、 刘继雄，王志奋，栾燕，陈士华，鞠新华，戴强，单以银，程丽杰，段莉萍，吴立新，李建华，《金相学术语》GB/T30067-2013，中华人民共和国国家标准，2013：1-101
最近发表的主要论文：
1.Jiarong Zhang, Yanfen Li, Feiyang Bao, Xiang Rui, Zhengang Duan, Wei Yan, Quanqiang Shi, Wei Wang, Yiyin Shan, Ke Yang. Study on the formation mechanism of Y-Ti-O oxides during mechanical milling and annealing treatment, Advanced Powder Technology (2021)
2.Ye Liang, Wei Yan, Xianbo Shi, Yanfen Li, Quanqiang Shi, Wei Wang, Yiyin Shan, Ke Yang. Study on W-rich M3B2 borides in a 9Cr3W3CoB heat-resistant steel, Journal of Materials Research and Technology 10(2021)594-604.
3.Guangquan Wang, Yanfen Li, Jiarong Zhang, Feiyang Bao, Yan Wei, Quanqiang Shi, Xianbo Shi, Yiyin Shan, Ke Yang. Design and preliminary characterization of a novel carbide-free 9Cr-ODS, Fusion Engineering and Design,160(2020)111824.
4.Chao Liu, Quanqiang Shi, Wei Yan, Chunguang Shen, Ke Yang, Yiyin Shan, Mingchun Zhao. Designing a high Si reduced activation ferritic/martensitic steel for nuclear power generation by using Calphad method. Journal of Materials Science & Technology. 35(2019)266-274.
5.Yiyin Shan, Hot Deformation Behavior of a New Nuclear Use Reduced Activation, the 19th International Conference on Fusion Reactor Materials (ICFRM-19), The University of California, Los Angeles, La Jolla, California. 2019.10.27-11.01.
6.Yanfen Li, Jiarong ZhangR, Yiyin Shan, Wei Yan, Quanqiang Shi, Ke Yang, J.J Shen, Nagasasa T, Muroga K, Yang H L, Kano S, Abe H. Anisotropy in creep properties and its microstructural origins of 12Cr oxide dispersion strengthened ferrite steels. 517(2019)307-214.
7.Xianbo. Shi, Wei Yan, Zhengguo Yang, Yi Ren, Yiyin Shan, Ke Yang, ffect of Cu alloying on strain capacity of Cu-bearing pipeline steels. ISIJ, Iternational,60(2019).
8.Chao Liu, Mingchun Zhao, Tuguldur Unenbayar, Yingchao Zhao, Bin Xie, Yan Tian, Yiyin Shan, Ke Yang. Hot Deformation Behavior of a New Reduced Activation Ferritic/Martensitic Steel. Acta Metallurgica Sinica (English Letters),7 (2019).
9.Le Zhang, Wei Wang, Shahzad M Babar, Yiyin Shan, KeYang. Hot Deformation Behavior of an Ultra-High-Strength Fe–Ni–Co-Based Maraging Steel. Acta Metallurgica Sinica (English Letters).9(2019)1161-1172.
10.Mengchao Niu, Gang Zhou, Wei Wang, M. Babar Shahzad, Yiyin Shan, Ke Yang. Precipitate evolution and strengthening behavior during aging process in a 2.5 GPa grade maraging steel. Acta Materialia,179(2019) 296-307.
11.Jialong Tian, Wei Wang, Huabing Li, M. Babar Shahzad, Yiyin Shan, Zhouhua Jiang, Ke Yang. Effect of deformation on precipitation hardening behavior of a maraging steel in the aging process, Materials Characterization 155(2019) 109827.
12.段贺, 单以银, 杨柯, 史显波, 严伟, 任毅. X80低温用高强度管线钢的工艺与组织性能试验研究, 钢铁, 55(2020)103-111.
13.杨柯, 史显波, 严伟, 曾云鹏, 单以银, 任毅. 新型含Cu管线钢——提高管线耐微生物腐蚀性能的新途径, 金属学报, 55 (2019).
14.杨柯, 梁烨, 严伟, 单以银. (9~12)%Cr马氏体耐热钢中微量B元素的择优分布行为及其对微观组织与力学性能的影响, 金属学报, 55(2020)53-65.
15.H. Wang, W. Yan, S.V. Zwaa, K. Yang, Yiyin Shan, On the 650℃ Thermostability of 9-12Cr Heat Resistant Steels Containing Different Precipitates. Acta Materialia, 2017, 134(1): 143-154.